October 5, 2025 |
PSY 448 Clinical Neuropsychology
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Day
Date
Class #
Topic
Readings & Other Assignments
Mo
Aug 25
01
General Introduction of both the class and of the class members
Discussion of Seminar Paper: Possible Topics
Syllabus
Topic Description Handout
Wondering
100 Trillion
Obiturary: Dr. Oliver Sacks 20150831 NYT
We Aug 27
02 Some Historical Principles and Notes about Neuropsychology A Brief Overview of Neuropsychology (Hevern)
Hutchins et al. (nd) Introduction to Neuroscience [UEN Digital Press with Pressbooks]
Meier (1992) Modern Clinical Neuropsychology in Historical Perspective [ LMC Only] [Google Scholar]
- Ancient Egyptians to European Renaissance
- Advances in Physiology, Histology, and Electricity Accelerate Understanding the Brain
- Localization of Function: Successes and Failures
Mo Sep 01
03 Behavioral Complexity: Aspects of Behavior
Full & Impaired Consciousness
Measuring/Predicting Survival with Brain Injury
Behaving: What Do Humans Do That Neuropsychologists Evaluate (I)
Barrett (2020) 7 1/2 Lessons Lesson 1/2 & Lesson 1 (pp. 1-28)
Full & Impaired Consciousness
Gosseries et al. (2011) [Download link] [Google Scholar]
Look particularly at figs. 2.1 and 2.2
Glasgow Coma Scale (GCS)
Predicting death from GCS (Perei et al, 2012)
Assessing the Severity of Traumatic Brain Injury (TBI):
Glasgow Coma Scale (GCS), the FOUR Score, and the CBI-M Framework
Behaving (Dimensions of Behavior, pdf)
We
Sep 03
04
Behaving: What Humans Do That Neuropsychologists Evaluate (II)
Barrett (2020) 7 1/2 Lessons Lessons 2-3 (pp. 29-63)Latin-Greek Vocabulary for Neuropsychology
Memory & Learning (Outline/Overview)
I will distribute in class an outline of Barrett's book by chapters which I have printed out (I'll also send it out on 9/2 for you to look over the first two or so pages). I would ask you to get up to speed reading what she has said. And, in class, I would like to discuss some of her major ideas about the brain.
I. Foundation: Behavior and Brain in Normal Functioning
Mo Sep 08
05
The "Normal Brain": A Brief Survey of Behavioral Anatomy
Orientation & Direction in the CNS
Major components: Layers of the Human Scull, Spinal Cord, Brainstem, Limbic System
Localization in the Neocortex: Functions of the Lobes (1)
[Note: in Clinical Neuropsychology we don't pay much attention to the cranial or autonomic nerves per se]
Due Today: Your Choices of Possible Presentation Topics and Possible Presentation DatesWe
Sep 10
06
Localization in the Neocortex: Functions of the Lobes (2)
Mo
Sep 15
07
(Class cancelled: Instructor illness)
We
Sep 17
08
(Class cancelled: Instructor illness)
Mo Sep 22 09
Modeling: What is the Human Brain for? Notes on Modeling 2023 (pdf, 14 pp.) [Summary]
Barrett (2020) 7 1/2 Lessons Lessons 4-5 (pp. 64-97)
We
Sep 24
10
How the Brain Gets Damaged: Basic Types of Neuropathology
(as a pdf file)
- Illness: Vascular Disorders, Tumors, Infection
- Injury: Traumatic Head Injury, Epilepsy
- Drugs-Alcohol-Chemical Toxicity
- Genetics: Inherited Degenerative Diseases
- Unknown: Alzheimer's Disease
Behavior Following Damage in/to the Brainstem, Midbrain, Cerebellum, Limbic System, Frontal & Temporal Lobes
How the Brain is Hurt (TBI Guide)
Subcortical, Cerebellar, & Limbic System Lesions: Behavioral Deficits
Frontal Lobe
Temporal Lobe
Mo
Oct 02
11
Behavioral Deficits: Parietal & Occipital Lobes; Insular Cortex Parietal Lobe
Occidental Lobe
Insula Cortex
III. Clinical Assessment: Looking at Behavior to Understand the Brain
We
Oct 04
12
Approaches to Neuropsychological Assessment
Psychometric Issues: Reliability, Validity, Standard Scores
Neuropsychological Examination: Procedures
Quantitative ("Normative") vs. Qualitative ("Process") Approaches
Neuropsychological Assessment, pt. 1 (Hevern, 2021 pdf)
Basic Psychometric Properties
Normal Curve & Standard Scores [graphic]
Commonly Used Neuropsychological TestsMo Oct 06 13
Wechsler Tests as a Foundation Intelligence as a Concept
WAISฎ-IV Wechlser Adult Intelligence Scale (4th ed., 2008)
Definitions of Intelligence (pdf)
- Overview of WAIS-IV (pdf brochure)
- Introducing the WAIS-IV (pdf presentation)
- Wikipedia overview of Wechsler tests {W}
Stratum IIWe
Oct 08
14
Wechsler Tests as a Foundation (cont'd)
- Exam #1 Take Home due today
Mo
Oct 13
Fall Break No Class
We
Oct 15
15
Flexible vs. Fixed Battery Approaches
Fixed Approaches
Fixed Batteries: Halstead-ReitanNeuropsychological Assessment, pt. 2 (Hevern, in pdf format)
- Notes on the Halstead-Reitan NTB (HRNTB, Hevern notes)
Mo
Oct 20
16
Individual Tests: Memory & Learning Memory & Learning (notes)
MoCA: Montreal Cognitive Assessment
CTVNews.ca (July 23, 2020)We
Oct 22
17
Individual Tests: Executive Functions & Language Executive Function Tests (notes)
Language (notes)Mo
Oct 27
18
Individual Tests: Personality Neuropsychological Assessment, pt. 3 Personality
(Hevern, in pdf format)
MMPI-3 (Pearson Assessment)
Ben-Porarth: Developing MMPI-3
Ben-Porath: Settings for UseWe
Oct 29
19
Brain Damage Epidemiology and Long-term Outcome across the Life Span
Handout on epidemiology & outcomes (7 pp. pdf)
IV. Student Presentations Mo Nov 03 20 TC Alcohol Use Disorder in Adolescence
Exam #2 (Take Home: Due: Wednesday, Nov 12)
We Nov 05 21 OM TBI among Soldiers and Veterans
HZ Parkinson's Disease
Mo
Nov 10
22 RA Toxic exposure in utero: lead, ETOH, tobacco
AL Long-term Outcome of Brain Damage in Children
We
Nov 12
23
EB Intellectual Disability
Exam #2 Take Home due todayTC Schizophrenia Spectrum Disorders
Mo
Nov 17
24
JL Autism Spectrum Disorder in Adults
KP Substance Use Disorder involving tobacco/vaping/nicotine/marijuana
We
Nov 19
25 TL Non-opioid Substance Abuse in Adolescents
JL Mood Disorders
Mo Nov 24
26 TM HIV Infection/AIDS
BS Alzheimer's Disease (Dementia)
We Nov 26
Thanksgiving Break No Class Mo Dec 04 27 SD Substance Use Disorder (Opioids, heroin, fentanyl)
RK Amyotropic Lateral Sclerosis ALS
We
Dec 06
28
Wednesday, December 10 Final Paper Due by 5 pm
References
Aliko, S., Wang, B., Small, S. L., & Skipper, J. I. (20230903) The entire brain, more or less is at work: Language regions are artefacts of averaging. BioRxiv. https://www.biorxiv.org/content/10.1101/2023.09.01.555886v1
- Note: The word artefact means "something observed in a scientific investigation or experiment that is not naturally present but occurs as a result of the preparative or investigative procedure" [Google Dictionary/Oxford Language]
Dworkin, J. D., Shinohara, R. T., & Bassett, D. S. (2018). The landscape of NeuroImage-ing research. NeuroImage. https://doi.org/10.1016/j.neuroimage.2018.09.005
Gosseries, O., Vanhaudenhuyse, A., et al. (2011) Disorders of consciousness: Coma, vegetative and minimally conscious states. In D. Cvetkovic & I. Cosic (Eds.), States of consciousness: Experimental insights into meditation, waking, sleeping, and dreams (pp. 29-55). Berlin, Germany: Springer-Verlag. [Download link]
Hay, P. J., Denson, L. A, van Hoof, M., & Blumenfeld. (2002). The neuropsychiatry of carbon monoxide poisoning in attempted suicide: A prospective controlled study. Journal of Psychosomatic Medicine, 53(2), 699-708. [LMC]
Kaufman, A. S. (2002). Do low levels of lead produce IQ loss in children? A careful examination of the literature. Archives of Clinical Neuropsychology, 16, 303-341. [LMC]
Meier, M. J. (1992). Modern clinical neuropsychology in historical perspective. American Psychologist, 47(4), 550-558. [LMC]
Summers, M. J. (2002). Neuropsychological consequences of right thalamic haemorrhage: Case study and review. Brain and Cognition, 50(1), 129-138. [LMC]
White, R. F., & Proctor, S. P. (1997, April 26). Solvents and neurotoxicity. The Lancet, 349, 1239-1243. [LMC]