Frédéric Swarts born 1866: organic fluorides; Swarts reaction. He was the first to prepare chlorofluorocarbons (CFCs): the first one he made was CFCl3, but he was also first to make CF2Cl2, the first CFC to become commercially important.
Luis Federico Leloir born 1906; biochemistry and metabolism of sugars, including the role of nucleotide sugars in carbohydrate biosynthesis; Nobel prize, 1970
Milestone case for forensic chemistry begins with the disappearance of a young German girl, later found murdered, in 1898. For the first time, chemical analysis of blood stains contributed to a conviction. (Look at a more recent blood analysis technique.)