BARBARA
BURACZYNSKI
Master of Science in Chemistry
(315)
699-0160
EDUCATION
TECHNICAL
M.S., Chemistry
1984
LE MOYNE COLLEGE,
MBA
WORK EXPERIENCE
ASSOCIATE SCIENTIST II Current-2005
Bristol-Myers
Squibb,
Biologic Quality Control (BQC)
ASSOCIATE SCIENTIST I 2004-2005
Bristol-Myers
Squibb,
Biologic Quality Control (BQC)
·
Ensure cGMP compliance in all aspects
of the analytical testing
·
Write, revise and implement SOPs and methods into BQC environment
·
Perform Sialic
Acid , Peptide Mapping, Neutral and Amino Monosaccharides,
N-linked oligosaccharide carbohydrate profiles analysis for release testing and
stability studies
·
Analyze, interpret and report analytical data (Empower/ Millennium)
·
Review and approve laboratory data
·
Conduct assay related trouble shooting
·
Troubleshooting, maintenance and calibration of HPLC and CE equipment
·
Perform and document instrumentation IQ/OQ/PQ
·
Participate in method transfer
·
Participate in the PAI inspection as a Subject Matter Expert
·
Providing training
ASSOCIATE SCIENTIST I 2002- 2004
Bristol-Myers
Squibb,
Analytical Biochemistry (AB)
ASISTANT SCIENTIST II 1998-2002
Bristol-Myers
Squibb,
Analytical Biochemistry (AB)
·
CTLA4Ig/LEA29Y Project Manager:
o
reviewing and releasing analyses results for all chromatographic
methods conducted in AB
o
established a database of results used for lot-to lot trending process
o
providing update on projects status for departmental meetings
o
providing data trending summaries for DCT meetings
o
assisting in creating
manufacturing sample pool plan for Fermentation and Purification Operations
o
creating and coordinating specific sample pool plan for validation of all analytical methods
performed in AB
o
working closely with Operational and Development personnel to
coordinate analyses for quick results turnaround
·
Perform testing to provide assay support for fermentation /
purification Manufacturing Operations and development activities using HPLC
(titer, SEC, sialic acid assays), spectrophotometric
and electrophoresis techniques in cGMP environment
·
Analyze, interpret and report analytical data (Waters Millennium, HP Chemstation)
·
Perform and document HPLC and UV Spectrophotometric
method development and validation studies
·
Perform and document instrumentation IQ/OQ/PQ
·
Troubleshooting, maintenance and calibration of HPLC equipment
·
Introduced to MOLDI-TOF Mass Spectrometry
·
Writing technical documents (SOPs, method protocols, validation
reports)
·
Providing and documenting training for new personnel
CONTRACT ANALYST 1997-1998
Bristol-Myers
Squibb,
Biotechnology Development Analytical Department
(BDAD)
·
Performing analyses of small molecules using HPLC systems (PenV/Poac, Des/Ceph C, Amphotericin B, Compactin P1)
LABORATORY ANALYST 1989-1992
Guelph Chemical Laboratories LTD,
·
Microanalyses of organic compounds for pharmaceutical industry with use
of chromatography, titration and spectrophotometry
techniques
·
Operation of analytical instruments such as CHN analyzer, UV
Spectrophotometer, Atomic Absorption Spectrophotometer
·
Compiling data and preparing
reports for customers
·
Maintaining records
CHEMICAL ENCHNEER/ PRODUCT
DEVELOPER 1985-1988
Wytwornia Materialow
z Tworzyw Sztucznych,
·
Product development (PVC floor covering)
·
Chemical process design and implementation into production
·
Production troubleshooting
·
Quality Control
STUDENT RESEACH AND DEVELOPMENT ASSOCIATION 1980-1984
Technical
·
Assistance in government sponsored research programs
·
Participate in development of new chemical process for industry
TECHNICAL SKILLS
· Extensive experience in following liquid chromatographic techniques:
o Size Exclusion Chromatography
o Ion Exchange Chromatography
o Affinity Chromatography
o Reverse Phase Chromatography
· Additional experience in:
o Capillary Electrophoresis
o UV Spectrophotometry
o Atomic Absorption Spectrophotometry
o Gel electrophoresis
o Elemental analysis (CHN Analyzer), familiar with MOLDI-TOF Mass Spectrometry.